The supplementation of vitamin B12 and folic acid in toddlers has reduced their plasma concentrations of fasting total homocysteine (tHcy) – an amino acid that is linked to cardiometabolic diseases when in elevated levels.
Chrononutrition has immense potential for improving cardiometabolic health by aligning food intake timings, calories and macronutrient distribution within the circadian rhythm, but more robust RCTs are urgently needed, claim researchers.